And the big worry that I have is that I have 2 screens and that when I open Mirillis Actions !, my 2 screens sintilles and 1 of 2 this cut and remains black and so I can only use myself, A single screen on the 2.

What's the minimum ATI/NVIDIA GPU combined with an Intel/AMD CPU needed for maximum quality without artifacts? I'm eager to ditch my CPU-bound smoother and leverage Motion2's CUDA acceleration.