Picture2 isn't working well on new generation video cards that have power management enabled. When Picture2 is activated, the card clocks constantly change from 3rd to 4th state causing little annoying stutters. Like for a few moments ( 40-50 ms ) the movie is in slow motion. I verified this with MSI Afterburner, because I didn't know why my movies play in slow motion over certain areas with P2 enabled and with MPC-HC play just fine.
nVIDIA ForceWare Clocks
Level #1 GPU: 50 MHz, Shader: 101 MHz, Memory: 135 MHz
Level #2 GPU: 405 MHz, Shader: 810 MHz, Memory: 324 MHz
Level #3 GPU: 405 MHz, Shader: 810 MHz, Memory: 1674 MHz
Level #4 GPU: 607 MHz, Shader: 1215 MHz, Memory: 1674 MHz